The Substance
2024HorrorEnglish141 min
A fading celebrity injects a black-market cell-replicating substance — and meets a younger, better version of herself. Demi Moore's fearless comeback, a body-horror masterpiece.
Official trailer on YouTube · Horror X Monsters · link verified 16 September 2026.
The story
A fading celebrity injects a black-market cell-replicating substance — and meets a younger, better version of herself. Demi Moore's fearless comeback, a body-horror masterpiece. Directed by Coralie Fargeat. With Demi Moore, Margaret Qualley, Dennis Quaid.